Research synthesis of polymeric supplies, emphasizing interrelationships of chemical pathways, course of circumstances, and microarchitecture of molecules produced. Chemical pathways embrace conventional approaches corresponding to anionic polymerization, radical condensation, and ring-opening polymerizations. Different methods are mentioned, together with steady free radical polymerizations and atom switch free radical polymerizations (ARTP), catalytic approaches to well-defined architectures, and polymer functionalization in bulk and at surfaces. Course of circumstances embrace bulk, answer, emulsion, suspension, fuel section, and batch vs. steady fluidized mattress. Microarchitecture consists of tacticity, molecular-weight distribution, sequence distributions in copolymers, errors in chains corresponding to branches, head-to-head addition, and peroxide incorporation.